General anesthesia is the most common type of anesthesia in both elective and emergency surgeries. Every day, many patients referred to clinics and hospitals are operated on under general anesthesia. Nitrous oxide is an inhalation anesthetic agent, which is commonly used in general anesthesia. Evidence suggests exposure to this anesthetic agent, either during an operation or constantly in the workplace (i.e. staff working in the operating room) can possibly cause various complications such as bone marrow suppression, polyneuropathy, postoperative nausea and vomiting, pulmonary hypertension and hyperhomocysteinemia. It is currently accepted that nitrous oxide inactivates cobalamin also known as vitamin B12, through irreversible oxidation of the cobalt atom of vitamin B12. This can lead to serious issues in individuals with low or borderline B12 levels that are undergoing general anesthesia where nitrous oxide is used.
Vitamin B9, more commonly known as folate (naturally occurring form of B9) or folic acid (a synthetic form), is a water-soluble vitamin that is part of the B vitamin family.
From supporting fetal development and growth to preventing cognitive decline and dementia, folate is essential throughout every stage of life.
It is best to get vitamin B9 from top Folate and Folic Acid Foods such as asparagus, avocados, brussels sprouts, and dark green leafy vegetables like spinach and lettuce, or beef liver and fortified rice. Named vegetables are even the namesake of folate; folate has the Latin word “folium” which literally means leaf, and these are healthy green foliage. However, folic acid can also be found in fortified breakfast cereals, flour, pasta, rice, beans, lentils, orange juice, broccoli, beef liver, and strawberries. So, what is the difference?
Methylcobalamin is slightly more biologically active than cyanocobalamin.
Both methylcobalamin and cyanocobalamin can treat vitamin B12 deficiency, and both will work for you*.
Cyano B12 is a cheap, synthetic, inactive form of B12 that is made with a cyanide donor and is used commercially. It is the most stable form, because the cyanide molecule has the greatest attraction to the cobalamin, so it protects it from conditions like very high temperatures. In fact, the average person in good health will not go wrong with either, remember getting more B12 can never be a bad thing. Methylcobalamin is one of the two active forms of vitamin B12.
Bottom line, in most case it is personal preference.
Now, whether you chew, drink, or swallow your vitamin the biggest issue is that the vitamin must survive the stomach acids and then the pancreatic fluids introduced in the small intestine, get absorbed by the intestine, and finally survive the liver-bypass metabolism that all food must go through when swallowed.
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