National Institute of Health (NIH) states that Vitamin D is considered a fat-soluble prohormone which is involved in many aspects of our wellbeing and regulatory functions just like a hormone. Everyone is aware that calcium absorption and bone health are major part of vitamin D benefits. However, most people may not know that Vitamin D is also involved in control of inflammation and immune response. Research has shown that vitamin D can interact with immune cells, affect genes that regulate inflammation, and alter the response of the immune system.
Vitamin D receptor (VDR) is present in most tissues and cells in the body. Vitamin D3 has a range of biological actions, such as inhibition of cellular proliferation, inducing terminal differentiation, inhibiting angiogenesis, stimulating insulin production, inhibiting renin production, and stimulating macrophage cathelicidin production. Vitamin D3 may be responsible for regulating up to 200 genes if not more that may facilitate many of the pleiotropic health benefits that have been reported for vitamin D3.
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